Prof. Dr. Ori Bar-Nur

Research area

The Laboratory of Regenerative and Movement Biology was launched on Feb 1^st 2018, as part of the Department of Health Sciences and Technology (D-HEST) at ETH Zurich. The primary scientific interest and long-term goal of the lab is to develop stem cell-based therapy approaches to treat degenerative loss of muscle mass in the form of muscular disorders, muscle injuries, and age-associated muscle wasting. To this end, we employ state-of-the-art mouse transgenic models, direct lineage reprogramming methods as well as stem cell lines cultured in vitro to dissect the molecular drivers that orchestrate skeletal muscle regeneration. Our lab is especially interested in elucidating the genetic and epigenetic changes that occur during cellular reprogramming, and the role transcription factors and signaling pathways play during the regeneration course.